| 产品详情 |
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| Antigenic Specificity | CD184 (CXCR4) |
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| Clone | 12G5 |
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| Host Species | Mouse |
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| Reactive Species | human, African green, baboon, chimpanzee, cynomolgus, rhesus, sooty mangabey |
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| Isotype | IgG2a, κ |
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| Format | Brilliant Violet 421™ conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Brilliant Violet 421™ anti-human CD184 (CXCR4). CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2. |
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| Immunogen | CP-MAC-infected Sup-T1 cells |
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| Other Names | CXCR4, Fusin |
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| Gene, Accession # | Gene ID: 7852 |
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| Catalog # | 306518 |
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| Price | |
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| Order / More Info | CD184 (CXCR4) Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 17289675,20231422,24554663,24814239 |
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