| 产品详情 |
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| Antigenic Specificity | mTOR |
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| Clone | 215Q18 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG2b, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | mTOR Monoclonal Antibody (215Q18). Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation. |
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| Immunogen | n/a |
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| Other Names | mTOR, MTOR, m-TOR, Mechanistic Target Of Rapamycin, Mammalian Target Of Rapamycin, FRAP, FRAP1, FRAP2, FK506 binding protein 12-rapamycin associated protein, FKBP-Rapamycin Associated Protein, Rapamycin Target Protein, Serine/Threonine-Protein Kinase MTOR, EC 2.7.11.1, RAFT1, RAPT1, mTORC1 |
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| Gene, Accession # | Entrez: 2475, 56717, 56718; Uniprot: P42345, P42346, Q9JLN9 |
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| Catalog # | AHO1232 |
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| Price | |
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| Order / More Info | mTOR Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 25270294, 27698900 |
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