| 产品详情 |
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| Antigenic Specificity | NPC1 |
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| Clone | CBWJN-1493 |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | IgG |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | WB, IHC-P, ICC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-NPC1 Recombinant Antibody (CBWJN-1493). This product is a Rabbit antibody that recognizes NPC1. The antibody CBWJN-1493 can be used for immunoassay techniques such as: WB, IHC-P, ICC. This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pi |
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| Immunogen | n/a |
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| Other Names | NPC Intracellular Cholesterol Transporter 1; Niemann-Pick Disease, Type C1; Truncated Niemann-Pick C1; Niemann-Pick C1 Protein; SLC65A1; NPC; |
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| Gene, Accession # | Gene ID: 4864, UniProt: O15118 |
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| Catalog # | CBMAB-N3107-WJ |
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| Price | |
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| Order / More Info | NPC1 Antibody from CREATIVE BIOLABS |
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| Product Specific References | n/a |
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| 产品资料 |
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