| 产品详情 |
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| Product Name | RK-33 |
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| Description | RK-33 is an inhibitor of DEAD box 3 (DDX3), an ATP-dependent RNA helicase. RK-33 inhibits the growth of lung cancer cells that overexpress DDX3 (IC50s = 4.4-8.4 µM) but is less effective in cells with low DDX3 expression (IC50 > 25 µM). It also promotes radiation sensitization in cells overexpressing DDX3. RK-33 in combination with radiation induces tumor regression in multiple animal models of lung cancer. MW: 428.45. Purity ≥98% by HPLC |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3,7-dihydro-3,7-bis[(4-methoxyphenyl)methyl]-2H-diimidazo[4,5-d:4',5'-f][1,3]diazepin-2-one |
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| Gene, Accession, CAS # | CAS: 1070773-09-9 |
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| Catalog # | B1273-25 |
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| Order / More Info | RK-33 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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