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| Product Name | TAT-cyclo-CLLFVY |
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| Description | Selective HIF-1 dimerization inhibitor. Blocks protein-protein interaction of recombinant HIF-1α, but not HIF-2α, with HIF-1β (IC50 = 1.3 μM). Inhibits hypoxia-induced HIF-1 activity, and decreases VEGF and CAIX expression in osteosarcoma and breast cancer cells in vitro. Also reduces tubularization of hypoxic HUVECs. MW (observed): 2559.1. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CAS: 1446322-66-2 |
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| Catalog # | 5582/1 |
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| Order / More Info | TAT-cyclo-CLLFVY from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23796364 |
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| 产品资料 |
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