| 产品详情 |
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| Antigenic Specificity | C. tetani TeNT Light Chain |
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| Clone | 604023 |
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| Host Species | Mouse |
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| Reactive Species | n/a |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Immunoprecipitation: 25 µg/mL, Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | C. tetani TeNT Light Chain Monoclonal Antibody (604023). Tetanus toxin, a member of the peptidase M27 family of proteins, is produced by the anaerobic spore-forming bacteria Clostridium tetani as a single-chain polypeptide that is 1315 amino acids (aa) in length. The protein is subsequently cleaved by an endogenous protease to yield the 52 kDa tetanus toxin light chain (TeNT-LC), which is 457 aa in length, and the 98 kDa tetanus toxin heavy chain that is 858 aa long. The light and heavy chains are linked by a disulfide bridge and are non-toxic after separation. Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neural synapses, is internalized and moves by retrograde transport up the axon into the spinal cord |
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| Immunogen | n/a |
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| Other Names | TeNT-LC; tetX; Tentoxylysin; Tetanus toxin chain H; Tetanus toxin chain L; Tetanus toxin heavy chain; Tetanus toxin light chain |
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| Gene, Accession # | n/a |
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| Catalog # | MA5-24273 |
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| Order / More Info | C. tetani TeNT Light Chain Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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