产品详情 |
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Product Name | Borrelidin |
Description | A macrolide antibiotic isolated from Streptomyces sp. An antiangiogenic (IC50 = 0.8 nM) agent. Bacterial and eukaryal threonyl-tRNA synthetase (THrRS) inhibitor. Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and induction of apoptosis. Also acts as a CDK inhibitor. MW: 489.64. Purity ≥98% by HPLC |
Size | 250 µg |
Concentration | n/a |
Applications | n/a |
Other Names | Treponemycin; U 78548; C2989 |
Gene, Accession, CAS # | CAS: 7184-60-3 |
Catalog # | 2367-250 |
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Order / More Info | Borrelidin from BIOVISION, INC. |
Product Specific References | n/a |
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