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| Product Name | Recombinant Human F-box only protein 3 (FBXO3) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 56.6kDa. Full Length: 1-471aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | FBXO3, UniProt: Q9UK99 |
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| Catalog # | RPC25570 |
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| Price | |
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| Order / More Info | Recombinant Human F-box only protein 3 (FBXO3) from BIOMATIK |
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| Product Specific References | n/a |
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