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| Product Name | Multidrug Resistance Assay Kit (Calcein AM) |
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| Description | Cayman's Multidrug Resistance Assay Kit provides a convenient tool for studying the modulation of cellular multidrug resistance (MDR) machinery. The kit employs calcein AM, a cell-permeable nonfluorescent dye, which is cleaved intracellularly to yield the impermeant fluorescent molecule, calcein. This calcein is rapidly excluded from cells expressing the MDR proteins P-gp or MRP, and so functions as a probe for the detection of chemical compounds inhibiting MDR proteins. Propidium iodide is provided as a stain for marking dead or damaged cells. Cyclosporin A, a competitive inhibitor of MDR proteins, and verapamil, a noncompetitive inhibitor, are included as controls. |
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| Size | 1 ea |
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| Concentration | n/a |
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| Applications | Flow Cytometry, Fluorescence |
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| Other Names | MDR |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 600370-1,000TESTS |
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| Order / More Info | Multidrug Resistance Assay Kit (Calcein AM) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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