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Product Name | TAPI-1 |
Description | Inhibitor of TNF-α processing (IC50 = 100 nM), similar to TAPI-0 (Cat. No. 2067-1), but more stable in tissue culture and in vivo. Inhibits TACE and other metalloproteases. Blocks release of TNF- α (IC50 = 50-100 µM), APP (1-8 µM), IL6R (5- 10 µM), TNFRI (5 -10 µM), TNFRII (25 -50 µM), and ObRa (leptin receptor), but not CSF-1, from cells in culture. MW: 499.3. Purity ≥95% by HPLC |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-naphthylalanyl-L-alanine amide; TNF protease inhibitor-0; C1 |
Gene, Accession, CAS # | CAS: 171235-71-5 |
Catalog # | 2068-1 |
Price | |
Order / More Info | TAPI-1 from BIOVISION, INC. |
Product Specific References | n/a |
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