| 产品详情 |
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| Product Name | CH 223191 |
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| Description | Potent aryl hydrocarbon receptor (AhR) antagonist (IC50 = 30 nM). Exhibits no AhR agonist-like activity (at concentrations up to 100 μM). Inhibits 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced AhR-dependent transcription in vitro and reduces TCDD-induced toxicity in vivo. Attenuates Th17 differentiation of naive CD4 T cells and promotes expansion of hematopoietic stem cells in vitro. Purity 98%. MW (observed): 333.39 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl-1H-pyrazole-5-carboxamide |
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| Gene, Accession, CAS # | CAS: 301326-22-7 |
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| Catalog # | 3858/10 |
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| Price | |
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| Order / More Info | CH 223191 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 22644306, 24165981, 26363006, 26426076, 27203850 |
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