| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Human IL-17A/F Heterodimer (carrier-free) |
|---|
| Description | IL-17A/F is part of the IL-17 cytokine family which consists of six structurally related proteins (IL-17A, B, C, D, E, and F). IL-17A is expressed primarily by Th17 cells, a subset of CD4 T cells. IL-17F is most closely related to IL-17A. The two molecules share 50% aminoacid sequence homology. Like IL-17A, IL-17F mRNA and protein have been detected in Th17 cells. IL-17F and IL-17A exist as a homodimers, adopting a cysteine knot motif formed through the interactions of four cysteines, one of which is responsible for the interchain bonding. IL-17F and IL-17A can form both homodimeric and heterodimeric proteins when expressed in a recombinant system and all forms of the recombinant proteins have in vitro functional activity. In addition, activated human CD4-T cells produce the homodimers of IL-17F, IL-17A, and the IL-17F/IL-17A heterodimer. |
|---|
| Size | 10 µg |
|---|
| Concentration | n/a |
|---|
| Applications | BA |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | Gene ID: 112744, 3605 |
|---|
| Catalog # | 580602 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human IL-17A/F Heterodimer (carrier-free) from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|