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| Product Name | SOS1, 564-1049aa, Human, His-tag, Baculovirus |
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| Description | MW: 58.0kDa (495aa) 50-70kDa (SDS-PAGE under reducing conditions.). Purity >95% by SDS-PAGE. SOS1, also known as son of sevenless homolog 1, is a Ras and Rac guanine nucleotide exchange factor. This protein is composed of several important domains. The CDC25 and REM domains provide the catalytic activity of SOS1 towards Ras and the histone fold DH/PH (Dbl homology and Pleckstrin homology) domains function, in tandem, to stimulate GTP/GDP exchange for Rac. Also, binding of GTP activates Ras prote |
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| Size | 0.02 mg, 0.1 mg |
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| Concentration | 0.25mg/ml (determined by Absorbance at 280nm) |
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| Applications | SDS-PAGE |
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| Other Names | [Son of sevenless homolog 1; SOS1; GF1; GGF1; GINGF; HGF; NS4] |
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| Gene, Accession, CAS # | SOS1, Gene ID: 6654, Accession: NP_005624 |
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| Catalog # | MBS206805 |
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| Order / More Info | SOS1, 564-1049aa, Human, His-tag, Baculovirus from MYBIOSOURCE INC. |
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| Product Specific References | Baruzzi A., et al, (2015) J. Immunol. 195:4900-4912. Lioubin MN., et al, (1994) Mol. Cell. Biol. 14:5682-5691. |
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