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| Product Name | PPARG, Recombinant, Human, aa1-477, His-Tag (Peroxisome Proliferator-activated Receptor gamma) |
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| Description | Purity ~90% (SDS-PAGE). Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels PDPK1 activates its transcriptional activity independently of its kinase activity. Source: Recombinant protein corresponding to aa1-477 from human PPARG, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~56.3kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Nuclear receptor subfamily 1 group C member 3 |
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| Gene, Accession, CAS # | SwissProt: P37231 |
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| Catalog # | 374809 |
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| Order / More Info | PPARG, Recombinant, Human, aa1-477, His-Tag (Peroxisome Proliferator-activated Receptor gamma) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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