| 产品详情 |
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| Product Name | PX 866 |
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| Description | A ring-opened analog of wortmannin that potently and irreversible inhibits PI3K (IC50 = 0.1-88 nM); less potently blocks the activity of mTOR (IC50 = 3.1 µM); exhibits single agent in vivo anti-tumor activity and increases the anti-tumor effects of cisplatin and radiation treatment |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | inhibitors inhibits inhibitions cancers kinases proteins signal transductions intracellular signaling signals PXs 866 PX-866 PX866 ring-opened rings opened opens analogs wortmannin PI3K in vivo anti-tumors anti tumors antitumors cisplatin radiation treatments reduces reduction cells growth motility cytotoxicity PI3-Kinase PI3 10010591irreversible potent blocks mammalian targets rapamycin 13346 single agents activity effects three-dimensional 3D three dimensional cultures dosing patients increases diseases stable |
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| Gene, Accession, CAS # | CAS: 502632-66-8 |
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| Catalog # | 13645-10 |
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| Price | |
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| Order / More Info | PX 866 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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