| 产品详情 |
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| Product Name | TL 13-112 |
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| Description | Selective anaplastic lymphoma kinase (ALK) degrader (DC50 values are 10 and 40 nM in H3122 and Karpas 299 cells, respectively). Comprises the cereblon E3 ligase ligand Pomalidomide (Cat. No. 6302) conjugated to an ALK inhibitor. Inhibits proliferation of ALK-positive cancer cell lines. Maximum degradation is exhibited at 16 h. Purity 98%. MW (observed): 1002.57 |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[2-[2-[2-[4-[4-[[5-Chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-1-piperidinyl]ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]acetamide |
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| Gene, Accession, CAS # | CAS: 2229037-19-6 |
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| Catalog # | 6745/5 |
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| Price | |
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| Order / More Info | TL 13-112 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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