| Edit |   |
|---|
| Antigenic Specificity | DR4 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | Cy3 conjugate |
|---|
| Size | 100ul |
|---|
| Concentration | 1ug/ul |
|---|
| Applications | IF(IHC-P) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | DR4 Polyclonal Antibody, Cy3 Conjugated. • Target Background: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. |
|---|
| Immunogen | KLH conjugated synthetic peptide derived from human DR4 . Immunogen Range: 420-468/468 |
|---|
| Other Names | DR4; APO2; CD261; TRAILR1; TRAILR-1; Tumor necrosis factor receptor superfamily member 10A; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; TNFRSF10A |
|---|
| Gene, Accession # | Gene ID: 8797, SwissProt: O00220 |
|---|
| Catalog # | bs-0591R-Cy3 |
|---|
| Price | |
|---|
| Order / More Info | DR4 Antibody from BIOSS ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|