| Edit |   |
| Antigenic Specificity | GPR65 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 100 µl |
| Concentration | n/a |
| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | GPR65 Polyclonal Antibody. GPR65 also known as TDAG8 is a transmembrane protein belonging to the G protein coupled receptor super family with 337-amino acid and 90% similarity and 81% identity in the 7 transmembrane domains of its mouse homolog. It has 3 potential N-linked glycosylation sites and is expressed predominantly in lymphoid organs and cancer tissues with increased expression during activation-induced death of T-cell hybridomas. Two major transcripts of 4.5 kb and 1.8 kb are found in peripheral blood leukocytes and functions as a novel proton-sensing receptor. It couples to adenylyl cyclase and psychosine and is also actively involved in the establishment of immunological autotolerance. GPR65 has a role in cellular transformation |
| Immunogen | n/a |
| Other Names | GPR65; G-protein coupled receptor 65; Gpcr25; HTDAG8; TDAG8; T-cell death-associated gene 8; Psychosine receptor; G protein-coupled receptor 65 |
| Gene, Accession # | Entrez: 8477; Uniprot: Q8IYL9 |
| Catalog # | PA5-65873 |
| Price | |
| Order / More Info | GPR65 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |