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Product Name | Recombinant Human TNF-Beta (E.coli-derived) Protein |
Description | TNF-β is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands and signals through TNFR1 and TNFR2. TNF-β is produced by activated T and B lymphocytes, and has similar activities to TNF-α. Like TNF-α, TNF-β is involved in the regulation of various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-β is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-β, which effectively anchors the TNF-β to the cell surface. TNF-β is cytotoxic to a wide range of tumor cells. Recombinant human TNF-β is a secreted 171 amino acid protein (18.6 kDa) which forms an active non-disulfide linked homotrimer structure in solution. |
Size | Various Sizes |
Concentration | n/a |
Applications | Cell Culture |
Other Names | Lymphotoxin-alpha;LT-alpha;TNF-beta;Tumor necrosis factor ligand superfamily member 1;LTA;TNFB, TNFSF1; Tumor Necrosis Factor-β, TNFSF1, Lymphotoxin-alpha (LT-α) |
Gene, Accession, CAS # | LTA, UniProt: P01374 |
Catalog # | PROTP01374-3 |
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Order / More Info | Recombinant Human TNF-Beta (E.coli-derived) Protein from BOSTER BIO |
Product Specific References | n/a |
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