| 产品详情 |
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| Antigenic Specificity | AXIN1 |
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| Clone | 11HCLC |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 2-5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | AXIN1 Antibody (11HCLC), ABfinity™ Rabbit Oligoclonal. The Axin (Axis Inhibition) protein is a ~120 kDa negative regulator of Wnt pathway signaling which is involved in regulation of embryonic axis development in vertebrates. In vertebrates, Wnt signaling occurs when the frizzled receptor transduces a signal to the Dishevelled protein, triggering glycogen synthase kinase-3 (GSK-3) inactivation and the accumulation of beta-catenin. Axin binds directly to GSK-3 beta, beta-catenin, and the adenomatous polyposis coli (APC) tumor suppressor protein at separate binding sites; these four proteins form a tetrameric complex that regulates beta-catenin stability and signaling. In addition to its role in Wnt signaling, Axin has been implicated i |
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| Immunogen | n/a |
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| Other Names | LA16c-314G4.3, AXIN, PPP1R49, axin-1, axis inhibition protein 1, axis inhibitor 1, fused, mouse, homolog of, protein phosphatase 1, regulatory subunit 49 |
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| Gene, Accession # | Entrez: 8312; Uniprot: O15169 |
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| Catalog # | 710204 |
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| Price | |
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| Order / More Info | AXIN1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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