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| Antigenic Specificity | Phospho-RSK Pan (Ser221, Ser227, Ser218, Ser232) |
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| Clone | 12H25L15 |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human, rhesus monkey |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-RSK Pan (Ser221, Ser227, Ser218, Ser232) Antibody (12H25L15), ABfinity™ Rabbit Monoclonal. The p90 ribosomal S6 kinases (RSKs) comprise a family of serine/threonine kinases that lie at the terminus of the ERK pathway. In humans, the RSK family consists of four isoforms (RSK1 to-4). RSK family members are unusual among serine/threonine kinases in that they contain two distinct kinase domains, both of which are catalytically functional. Theses kinase domains are activated in a sequential manner by a series of phosphorylations. RSK regulates gene expression via association and phosphorylation of transcriptional regulators including c-Fos, estrogen receptor, NFkappaB/IkappaB alpha, cAMP-response element-binding protein (CREB). ERK |
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| Immunogen | n/a |
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| Other Names | MAPKAPK1A, RSK1 |
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| Gene, Accession # | Entrez: 6195, 6196, 6197, 696825, 714794, 716899, 717574, 8986; Uniprot: O75676, P51812, Q15349, Q15418 |
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| Catalog # | 702304 |
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| Order / More Info | Phospho-RSK Pan (Ser221, Ser227, Ser218, Ser232) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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