| 产品详情 |
| Edit |   |
|---|
| Product Name | Neutrophil Elastase Activity Assay kit (Fluorometric) |
|---|
| Description | Neutrophil Elastase (NE, EC 3.4.21.37, leukocyte elastase, elastase 2, or serine elastase) is a cytotoxic serine protease. It is stored in the azurophil granules of neutrophil granulocyte and is released following cell stimulation, e.g. by pathogens, immune complexes or chemotactic agents (PMA). When the extracellular NE concentration exceeds the buffering capacity of endogenous inhibitors, it causes degradation of a wide range of extracellular matrix proteins, including fibronectin, laminin, proteoglycans, collagens, and elastin. Extracellular elastase is implicated in the signs, symptoms and disease progression of inflammatory lung disorders (such as cystic fibrosis, COPD, lung emphysema) via its role in the inflammatory processes, mucus |
|---|
| Size | 100 assays |
|---|
| Concentration | n/a |
|---|
| Applications | • Determine activity of purified Neutrophil Elastase• Detect the activity of Neutrophil Elastase in plasma, blood• Screen/study/characterize chemotactic agents causing Neutrophil stimulation and release of Elastase |
|---|
| Other Names | Leukocyte Elastase Activity Assay kit (Fluorometric) , Elastase 2 Activity Assay kit (Fluorometric) , Serine Elastase Activity Assay kit (Fluorometric) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | K383-100 |
|---|
| Price | |
|---|
| Order / More Info | Neutrophil Elastase Activity Assay kit (Fluorometric) from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|