| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Human Fibroblast growth factor 7 protein (FGF7) (Active) |
|---|
| Description | Purity > 95% as determined by SDS-PAGE. MW: 12.46kDa. Extracellular Domain: 24-126aa. C-terminal 6xHis-tagged. Homo sapiens (Human). Activin Receptor Type-1B (ACVR1B) is a single-pass type I membrane protein that belongs to the protein kinase superfamily. ACVR1B contains one GS domain and one protein kinase domain and is expressed in many tissues, most strongly in kidney, pancreas, brain, lung, and liver. ACVR1B acts as a transducer of activin or activin like ligands signals. Activin binds to either ACVR2A or ACVR2B and then forms a complex with ACVR1B, ACVR2A or ACVR2B activating ACVR1B through phosphorylation of its regulatory GS domain. They go on to recruit the R-SMADs, SMAD2 and SMAD3. ACVR1B also transducers signals of nodal, GDF-1, and Vg1. Mutations in ACVR1B are associated with pituitary tumors. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | Activin Receptor Type-1B; Activin Receptor Type IB; ACTR-IB; Activin Receptor-Like Kinase 4; ALK-4; Serine/Threonine-Protein Kinase Receptor R2; SKR2; ACVR1B; ACVRLK4; ALK4 |
|---|
| Gene, Accession, CAS # | ACVR1B, UniProt: P36896 |
|---|
| Catalog # | RPC26982 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human Fibroblast growth factor 7 protein (FGF7) (Active) from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|