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| Product Name | GSK-690693 HCl |
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| Description | MW: 426. Purity 99% (HPLC); NMR (Conforms). AKT inhibitorPotent and selective inhibitor of Src family tyrosine kinases. IC50=5 nM (p65lck), IC50=6 nM(P59fynT), IC50=170 nM (p60src). Cell permeable.Scientific Background: A novel ATP-competitive pan-specific Akt kinase inhibitor. (IC50s=2, 13, 9 nM for Akt1, 2 and 3 respectively)(1). Antitumor activity. Active in vivo. Induces hyperglycemia (2). Cell permeable. |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [PP1; 4-Amino-1-tert-butyl-3-(4-methylphenyl) pyrazolo [3,4-d] pyrimidine; (S)-4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol. HCl ] |
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| Gene, Accession, CAS # | CAS: 937174-76-0 |
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| Catalog # | MBS515016 |
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| Price | |
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| Order / More Info | GSK-690693 HCl from MYBIOSOURCE INC. |
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| Product Specific References | 1. JH Hanke et al J. Biol. Chem 1996 271:695 |
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