| 产品详情 |
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| Product Name | GSK J4 |
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| Description | Histone lysine demethylase (KDM) inhibitor; blocks demethylation of histone H3K27. Attenuates lipopolysaccharide (LPS)-induced proinflammatory cytokine production in primary human macrophages (IC50 = 9 μM for the inhibition of TNFα release). Cell permeable. Ethyl ester derivative of GSK J1. Negative Control also available.. Purity 99%. MW (observed): 417.5 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester |
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| Gene, Accession, CAS # | CAS: 1373423-53-0 |
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| Catalog # | 4594/10 |
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| Price | |
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| Order / More Info | GSK J4 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 24276476, 25487152, 25652587, 25671108, 26263556, 26625958, 27010597, 27581455 |
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| 产品资料 |
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