| 产品详情 |
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| Antigenic Specificity | TIGIT |
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| Clone | A15153G |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a, κ |
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| Format | TotalSeq™-B oligomer conjugate |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | Proteogenomics. TotalSeq™ reagents are designed to profile protein expression at a single cell level following an optimized protocol similar to the CITE-seq workflow. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TotalSeq™-B0089 anti-human TIGIT (VSTM3). T cell immunoreceptor with Ig and ITIM domains (TIGIT), also known as VSTM3 or WUCAM, is a 26 kD, type I transmembrane protein and is a member of the PVR (poliovirus receptor) family of immunoglobulin-like domain containing proteins. TIGIT is expressed on activated T cells, follicular T helper, memory, and regulatory T cells as well as on NK cells. TIGIT is a negative regulator of NK and T cell activation. Expression of TIGIT is associated with decreased functionality of CD8 T cells in chronic viral infection and tumors. TIGIT also promotes the differentiation of tolerogenic phenotype in dendritic cells with an increased secretion of IL-10 and a diminished production of IL-12. |
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| Immunogen | Recombinant Human TIGIT. |
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| Other Names | T-cell immunoreceptor with Ig and ITIM domains, VSIG9, VSTM3, WUCAM |
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| Gene, Accession # | Gene ID: 201633 |
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| Catalog # | 372727 |
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| Price | |
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| Order / More Info | TIGIT Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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