| 产品详情 |
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| Product Name | Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1) peptide |
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| Description | Apbb1 is an adapter protein that forms a transcriptionally active complex with the gamma-secretase-derived amyloid precursor protein (APP) intracellular domain.Apbb1 plays a central role in the response to DNA damage by translocating to the nucleus and inducing apoptosis. Apbb1 may act by specifically recognizing and binding histone H2AX phosphorylated on 'Tyr-142' (H2AXY142ph) at double-strand breaks (DSBs), recruiting other pro-apoptosis factors such as MAPK8/JNK1. |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
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| Other Names | apbb1|MGC80654|Fe65|Rir|FE65|MGC:9072|RIR |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN937349 |
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| Order / More Info | Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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| 产品资料 |
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