| 产品详情 |
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| Antigenic Specificity | p19ARF |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat |
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| Isotype | n/a |
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| Format | biotin conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, IHC-P |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | p19ARF Polyclonal Antibody, Biotin Conjugated. • Target Background: P19ARF Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. Binds to BCL6 and down-regulates BCL6-induc |
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| Immunogen | KLH conjugated synthetic peptide derived from Rat P19ARF. Immunogen Range: 120-160/160 |
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| Other Names | Cyclin-dependent kinase inhibitor 2A; isoform 2; p19ARF; Cdkn2a |
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| Gene, Accession # | Gene ID: 12578, SwissProt: Q64364 |
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| Catalog # | bs-0534R-Biotin |
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| Price | |
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| Order / More Info | p19ARF Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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