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Product Name | Recombinant Human C-C chemokine receptor type 4 (CCR4) |
Description | Purity > 85% as determined by SDS-PAGE. MW: 44.9kDa. Full Length: 1-360aa. N-terminal 10xHis-tagged. Homo sapiens (Human). High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G (i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | K5-5; CD_antigen: CD194 |
Gene, Accession, CAS # | CCR4, UniProt: P51679 |
Catalog # | RPC20710 |
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Order / More Info | Recombinant Human C-C chemokine receptor type 4 (CCR4) from BIOMATIK |
Product Specific References | n/a |
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