| 产品详情 |
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| Antigenic Specificity | CATSPER1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CATSPER1 Polyclonal Antibody. CatSper is an ion transport protein located on the surface of sperm cells. CatSper (for cation channel of sperm) is vital to cAMP-mediated calcium influx in sperm, sperm motility and fertilization. The gene that encodes CatSper maps to human chromosome 11q12.1. The 686 amino acid protein is a single, six-transmembrane-spanning protein of the voltage- dependent Ca2+ channel four-repeat structure and is expressed exclusively in the testis. In CatSper -/- sperm, neither cAMP nor cGMP elicit a significant Ca2+ influx in both mutant and wild-type sperm. CatSper is localized to the sperm flagellum and CatSper -/- mice show sluggish and less directed movements. CatSper is required to penetrate the egg, but is not requ |
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| Immunogen | n/a |
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| Other Names | Cation channel sperm-associated protein 1; CatSper1; hCatSper; CATSPER1 |
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| Gene, Accession # | Entrez: 117144, 225865, 689349; Uniprot: Q8NEC5, Q91ZR5 |
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| Catalog # | PA5-75788 |
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| Price | |
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| Order / More Info | CATSPER1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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