| 产品详情 |
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| Product Name | Recombinant Human CCR4-NOT transcription complex subunit 8 (CNOT8) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 60.5kDa. Full Length: 1-292aa. N-terminal GST-tagged. Homo sapiens (Human). Has 3'-5' poly (A) exoribonuclease activity for synthetic poly (A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | CAF1-like protein |
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| Gene, Accession, CAS # | CNOT8, UniProt: Q9UFF9 |
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| Catalog # | RPC23600 |
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| Order / More Info | Recombinant Human CCR4-NOT transcription complex subunit 8 (CNOT8) from BIOMATIK |
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| Product Specific References | n/a |
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