| 产品详情 |
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| Antigenic Specificity | HAKAI |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 ul |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit polyclonal to HAKAI.HAKAI is also known as Casitas B-lineage lymphoma-transforming sequence-like protein 1 (CBLL1),which is an E3 ubiquitin-protein ligase for the E-cadherin (CDH1) complex and mediates itsubiquitination, endocytosis, and degradation in the lysosomes. CDH1 is endocytosed as aconsequence of tyrosine phosphorylation and ubiquitination. HAKAI interacts with tyrosinephosphorylatedCDH1 and mediates this process. HAKAI contains a RING-finger domain and is alsothought to have a role in the control of cell proliferation. |
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| Immunogen | C-terminal region of human HAKAI |
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| Other Names | HAKAI,E3 ubiquitinprotein ligase Hakai,Casitas Blineage lymphomatransforming sequencelike protein 1,RING finger protein 188,RNF188,cCbllike protein 1,CBLL1 |
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| Gene, Accession # | UniProt: Q75N03 |
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| Catalog # | orb67187 |
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| Price | |
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| Order / More Info | HAKAI Antibody from BIORBYT LTD. |
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| Product Specific References | n/a |
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