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| Product Name | Factor Va, Human Plasma |
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| Description | Factor Va is a cofactor for the serine protease factor Xa, and in the presence of calcium ions they collectively assemble on a phospholipid surface to form the prothrombinase complex. The prothrombinase complex is responsible for the rapid conversion of prothrombin to thrombin. Factor Va is derived from the pro-cofactor, factor V, upon limited proteolysis by alpha-thrombin. The thrombin cleavage of factor V liberates two heavily glycosylated activation peptides from the central portion of the molecule which have no cofactor function. Factor Va is comprised of an NH2-terminal derived heavy chain (Mr=94,000) and a COOH-terminal derived light chain (Mr=74,000) which remain associated in the presence of calcium ions. The cofactor binds to phosp |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Activated protein C cofactor, Proaccelerin (labile factor) |
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| Gene, Accession, CAS # | F5, Gene ID: 2153, Accession: P12259 |
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| Catalog # | 4098-10 |
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| Order / More Info | Factor Va, Human Plasma from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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