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| Product Name | 4-Methylumbelliferyl Beta-D-Galactopyranoside-6-sulfate (sodium salt) |
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| Description | Purity >98%. 4-Methylumbelliferyl Beta-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N -acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-methyl-7-[(6-O-sulfo-Beta-D-galactopyranosyl)oxy]-2H-1-benzopyran-2-one, monosodium salt, 4-Methylumbelliferyl Gal-6S, 4-MU -Beta-D-galactopyranoside-6-sulfate, 4-MU-Gal-6S |
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| Gene, Accession, CAS # | CAS: 206443-06-3 |
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| Catalog # | LS-H6140 |
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| Order / More Info | 4-Methylumbelliferyl Beta-D-Galactopyranoside-6-sulfate (sodium salt) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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