| 产品详情 |
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| Antigenic Specificity | MUC1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | IHC, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal Picoband™ antibody for Mucin-1(MUC1) detection. Tested with WB, IHC-P, IHC-F in Mouse;Rat. No cross reactivity with other proteins. Mucin 1, cell surface associated (MUC1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans. This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. It is mapped to 1q22. Mucin 1 is a transmembrane mucin normally expressed on the apical borders of secretory epithelial cells. Overexpression of Mucin 1 is often associated with colon, breast, ovarian, lung and pancreatic cancers. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Mucin 1 stimulated ESR1-mediated transcription and contributed to estradiol-mediated growth and survival of breast cancer cells. This gene also can suppress pulmonary innate immunity, and its antiinflammatory activity may play an important modulatory role during microbial infection. |
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| Immunogen | E.coli-derived mouse MUC1 recombinant protein (Position: S474-L630). Mouse MUC1 shares 87% and amino acid (aa) sequence identity with human MUC1. |
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| Other Names | Mucin-1;MUC-1;Episialin;CD227;Mucin-1 subunit alpha;MUC1-NT;MUC1-alpha;Mucin-1 subunit beta;MUC1-beta;MUC1-CT;Muc1;Muc-1; |
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| Gene, Accession # | MUC1, MUC1, UniProt: Q02496 |
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| Catalog # | PB9112 |
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| Price | |
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| Order / More Info | MUC1 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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