| 产品详情 |
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| Antigenic Specificity | Caspase-1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | 0.2 mg/ml |
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| Applications | Western blot, Immunoprecipitation, Immunofluorescence |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase-1 Antibody. Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-1 (ICE, interleukin-1β-converting enzyme) is the mammalian caspase responsible for the proteolytic conversion of the proforms of interleukin-1β and IL-18 into active cytokines. Like other caspases, Caspase-1 itself is synthesized as a pro-enzyme that is cleaved during activation into a large (20 kDa) and small (10 kDa) subunits. The cellular role of caspase-1 appears limited to cytokine activation as they do not have obvious roles in apoptosis. |
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| Immunogen | Synthetic peptide surrounding amino acid 132 of human caspase-1 |
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| Other Names | CASP1, IL1BCE, P45, Interleukin-1 beta convertase, IL-1BC, IL1BC, p45, IL1B-convertase, CASP-1, ICE |
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| Gene, Accession # | Gene ID: 834, Accession: NP_150636 |
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| Catalog # | 3019-100 |
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| Price | |
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| Order / More Info | Caspase-1 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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