| 产品详情 |
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| Product Name | ELR510444 |
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| Description | An inhibitor of tubulin polymerization (IC50 = 10 µM); binds to tubulin at the colchicine binding site; induces microtubule depolymerization in A-10 cells (EC50 = 21 nM); inhibits growth in a cancer cell line panel (IC50s = 9-43 nM) via formation of multiple spindles and induction of mitotic arrest; reduces tumor size in an MDA-MB-231 breast cancer mouse xenograft model in a dose-dependent manner; inhibits HIF-1α in RCC4 cells in a concentration-dependent manner, |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ELR-510444 A10 MDAMB-231 MDAMB231 HIF1α HIF1a RCC-4 |
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| Gene, Accession, CAS # | CAS: 1233948-35-0 |
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| Catalog # | 17696-10 |
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| Price | |
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| Order / More Info | ELR510444 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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