| 产品详情 |
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| Antigenic Specificity | PPP4C |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 2-4 µg/mL, peptide-ELISA: 1:16000, Western Blot: 0.1-0.3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PPP4C Polyclonal Antibody. Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interpha |
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| Immunogen | n/a |
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| Other Names | PPP4C; protein phosphatase 4 (formerly X), catalytic subunit; PP4; PPH3; PPX; Protein phosphatase 4, catalytic subunit |
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| Gene, Accession # | Entrez: 171366, 5531; Uniprot: P60510, Q5BJ92 |
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| Catalog # | PA5-19132 |
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| Price | |
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| Order / More Info | PPP4C Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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