| 产品详情 |
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| Antigenic Specificity | TOP3A |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TOP3A Polyclonal Antibody. DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA by transiently breaking and rejoining DNA strands. Although DNA topoisomerase I (Topo I) and Topo II relax both positive and negative supercoils, Topo III relaxes only negative supercoils. Topo IIIα exists as a long and a short isoform, which are produced by alternative splicing. Topo IIIα, which localizes to the nucleolus, is constitutively expressed and remains at high levels throughout the cell cycle in HL-60 cells. Topo IIIβ exists as three isoforms,β-1,β -2 and β-3, also produced by alternative splicing. Topo IIIβ-1 is expressed in testis, heart, and skeletal muscle, whereas Topo III&beta |
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| Immunogen | n/a |
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| Other Names | DNA topoisomerase 3-alpha; DNA topoisomerase III alpha; TOP3A; TOP3 |
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| Gene, Accession # | Entrez: 7156; Uniprot: Q13472 |
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| Catalog # | PA5-75799 |
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| Price | |
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| Order / More Info | TOP3A Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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