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| Product Name | Elongin B, 1-118aa, Human, E Coli |
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| Description | MW: 13.1 kDa (118 aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. Elongin B, also known as TCEB2, is a subunit of the transcription factor B (SIII) complex. The SIII complex is a heterotrimer consisting of a transcriptionally active subunit (A) and two regulatory subunits (B and C). It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. The von Hippel-Lindau tumor suppressor protein (pVHL) binds to elongins |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Elongin B; Transcription elongation factor B polypeptide 2; TCEB2; RNA polymerase II transcription factor SIII subunit B; SIII p18; EloB; Elongin 18 kDa subunit; EloB; TCEB 2; Transcription elongation factor B (SIII) polypeptide 2.] |
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| Gene, Accession, CAS # | ELOB; ELOB; SIII; TCEB2; EloB, Gene ID: 6923, Accession: NP_009039 |
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| Catalog # | MBS203206 |
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| Order / More Info | Elongin B, 1-118aa, Human, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Piessevaux J., et al. (2008) J Biol Chem. 283 (31):21334-46.; Duan DR., et al. (1995) Science. 269 (5229):1402-6; |
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