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Product Name | Recombinant Protobothrops flavoviridis Thrombin-like enzyme flavoxobin (TLF1) |
Description | Purity > 85% as determined by SDS-PAGE. MW: 33.1kDa. Full Length of Mature Protein: 25-260aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Protobothrops flavoviridis (Habu) (Trimeresurus flavoviridis). Thrombin-like snake venom serine protease that clots fibrinogen by releasing fibrinopeptide A. According to PubMed:8585090, only cleaves rabbit fibrinogen, whereas no specificity is described in PubMed:3910643. Also acts as a C3 convertase that independently cleaves human C3 and kick-starts the complement cascade. Also increases urokinase-type plasminogen activator and plasminogen activator inhibitor in cultured bovine pulmonary artery endothelial cells. Dose-dependently inhibits collagen-induced platelet aggregation. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Fibrinogen-clotting enzyme (Habutobin) (Snake venom serine protease 1) (SVSP) (SVTLE) |
Gene, Accession, CAS # | TLF1, UniProt: P05620 |
Catalog # | RPC26245 |
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Order / More Info | Recombinant Protobothrops flavoviridis Thrombin-like enzyme flavoxobin (TLF1) from BIOMATIK |
Product Specific References | n/a |
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