| 产品详情 |
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| Antigenic Specificity | CD146 |
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| Clone | P1H12 |
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| Host Species | Mouse |
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| Reactive Species | canine, human, mouse, rabbit |
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| Isotype | IgG1, kappa |
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| Format | eFluor 450 conjugate |
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| Size | 25 Tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 5 µL (0.125 µg)/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD146 Monoclonal Antibody (P1H12), eFluor 450, eBioscience™. CD146 (MCAM) is an integral membrane glycoprotein belonging to the immunoglobulin superfamily. CD146 is expressed at cell-cell junctions in all endothelial cells, and has also been observed in other normal and malignant cell types. In addition to its recognized role as a calcium-independent cell adhesion molecule, CD146 may also act as a signal transduction molecule in the recruitment of Fyn kinase, and in the subsequent tyrosine-phosphorylation of intracellular proteins involved in actin cytoskeleton assembly. CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. CD146 expression may allow melanoma c |
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| Immunogen | n/a |
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| Other Names | CD146; cell surface glycoprotein MUC18; cell surface glycoprotein P1H12; Gicerin; MCAM; melanoma adhesion molecule; melanoma-associated antigen A32; melanoma-associated antigen MUC18; MUC18; S-endo 1 endothelial-associated antigen |
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| Gene, Accession # | Entrez: 100342848, 4162, 489368, 84004; Uniprot: P43121, Q8R2Y2 |
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| Catalog # | 48-1469-41 |
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| Price | |
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| Order / More Info | CD146 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 22676440, 27068890, 28928360 |
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