| 产品详情 |
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| Antigenic Specificity | NMDAR1 |
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| Clone | 54.1 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, nonhuman primate, rat |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: 0.1-1 µg/mL, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (Paraffin): 1:10-1:50, Immunoprecipitation: 1-3 µg/mL, Western Blot: 1-5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NMDAR1 Monoclonal Antibody (54.1). N-methyl-D-aspartate (NMDA) type receptors are glutamate-gated ion channels that possess high-calcium permeability and voltage-dependent sensitivity to magnesium, and play a central role in brain function and disease. Activation of NMDA receptors, in the presence of NMDA, glutamate, and glycine, leads to elevations in synaptic calcium levels, initiating a series of calcium-dependent signaling events including activation of nitric oxide synthase, stimulation of calcium/calmodulin-dependent protein kinase, and MAP kinase cascades. Through these signal transduction pathways, NMDA receptors mediate synaptic plasticity, synaptogenesis, excitotoxicity, and memory acquisition and learning. NMDA receptors are comp |
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| Immunogen | n/a |
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| Other Names | GLURZ1, GRIN1, Glutamate [NMDA] receptor subunit zeta 1 precursor, N-methyl-D-aspartate receptor, NMD-R1, NMDZ1, NMZ1, NR1, pGluN1 |
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| Gene, Accession # | Entrez: 14810, 24408, 2902; Uniprot: P35438, P35439, Q05586 |
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| Catalog # | 32-0500 |
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| Price | |
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| Order / More Info | NMDAR1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12691775, 12732245, 15814786, 17067377, 18094256, 18755203, 20345922, 20639432, 21220022, 21406232, 21935408, 22285407, 22740692, 24667777, 25131692, 26041915, 26341392, 27117477, 27338016, 27457704, 8207476, 8290563, 8813384, 9619504 |
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