| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Mouse Endoplasmic reticulum aminopeptidase 1 (Erap1), partial |
|---|
| Description | Purity > 90% as determined by SDS-PAGE. MW: 28.3kDa. Partial: 731-930aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Mus musculus (Mouse). Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney (By similarity). |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | ARTS-1; Adipocyte-derived leucine aminopeptidase |
|---|
| Gene, Accession, CAS # | Erap1, UniProt: Q9EQH2 |
|---|
| Catalog # | RPC21275 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Mouse Endoplasmic reticulum aminopeptidase 1 (Erap1), partial from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|