| 产品详情 |
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| Antigenic Specificity | Complement C4 |
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| Clone | 49H9 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Immunoprecipitation: 1 µL, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Complement C4 Monoclonal Antibody (49H9). This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster |
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| Immunogen | n/a |
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| Other Names | DAMC-258G8.6, C4, C4A2, C4A3, C4A4, C4A6, C4S, CO4, CPAMD2, MGC164979, RG |
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| Gene, Accession # | Entrez: 720; Uniprot: P0C0L4 |
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| Catalog # | LF-MA0188 |
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| Price | |
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| Order / More Info | Complement C4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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