| 产品详情 |
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| Antigenic Specificity | Complement C4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 2 mL |
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| Concentration | n/a |
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| Applications | Immunofluorescence: Neat |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Complement C4 Polyclonal Antibody. This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, |
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| Immunogen | n/a |
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| Other Names | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2, C4A anaphylatoxin,Rodgers form of C4, acidic C4, acidic complement C4, complement C4-A |
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| Gene, Accession # | Entrez: 720; Uniprot: P0C0L4 |
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| Catalog # | PA5-16602 |
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| Price | |
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| Order / More Info | Complement C4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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