| 产品详情 |
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| Antigenic Specificity | ZC3H8 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µl |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:10-1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ZC3H8 Polyclonal Antibody. Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis. |
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| Immunogen | n/a |
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| Other Names | Zinc finger CCCH domain-containing protein 8, ZC3H8, ZC3HDC8 |
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| Gene, Accession # | Entrez: 57432, 84524; Uniprot: Q8N5P1, Q9JJ48 |
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| Catalog # | PA5-48207 |
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| Price | |
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| Order / More Info | ZC3H8 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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