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| Antigenic Specificity | CCDC36 |
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| Clone | OTI2D11 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CCDC36 Monoclonal Antibody (OTI2D11). Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance. |
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| Immunogen | n/a |
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| Other Names | CCDC36; Coiled-coil domain-containing protein 36; Cancer/testis antigen 74 |
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| Gene, Accession # | Entrez: 339834; Uniprot: Q8IYA8 |
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| Catalog # | MA5-26980 |
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| Price | |
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| Order / More Info | CCDC36 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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