| 产品详情 |
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| Antigenic Specificity | PREB |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, canine, equine, guinea pig, human, mouse, porcine, rabbit, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 4-8 µg/mL, Western Blot: 0.2-1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PREB Polyclonal Antibody. Prolactin (PRL) expression in the pituitary is limited to specific cells. Pit-1 is a pituitary specific transcription factor that plays an important role in PRL expression, both in mature organism and during development. The PRL promoter contains numerous Pit-1 binding sites and these sites have been implicated in both basal level and kinase-mediated gene expression. The most proximal of these binding sites, termed 1P, has been shown to direct a response to numerous signals, such as cAMP and various G-proteins. A novel protein, termed PREB (prolactin regulatory element binding protein), has been recently identified that regulates PRL gene expression through the 1P site, though it contains no discernable DNA-binding |
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| Immunogen | n/a |
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| Other Names | Prolactin regulatory element binding, SEC12 |
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| Gene, Accession # | Entrez: 100071281, 100350980, 100522734, 100721438, 10113, 483007, 50907, 525256, 58842; Uniprot: Q9HCU5, Q9WTV0, Q9WUQ2 |
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| Catalog # | PA5-40828 |
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| Price | |
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| Order / More Info | PREB Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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