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| Product Name | PKC iota, Active |
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| Description | PKC ι is a member of the protein kinase C family of serine-threonine kinases. The amino acid sequence of PKC ι showed greatest homology to PKC zeta, with 72% identity overall rising to 84% in the catalytic domain. In contrast, the homology of PKC ι to the other isoforms is less pronounced, with < 53% identity even in the highly conserved catalytic region. PKC ι transcript is present predominantly in lung and brain, but also expressed at lower levels in many tissues including pancreatic islets. PKC ι is stimulated by tumor necrosis factor α (TNF-α) and is required for the activation of NF-kB by this cytokine. Cell transfections with a PKC ι dominant negative mutant abolished TNF-α-induced NFkB- |
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| Size | 5 µg |
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| Concentration | 5µg/50 µl |
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| Applications | RUO |
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| Other Names | PKC, Protein kinase C iota |
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| Gene, Accession, CAS # | PRKC1, Gene ID: 5584, Accession: NM_002740 |
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| Catalog # | 7705-5 |
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| Order / More Info | PKC iota, Active from BIOVISION, INC. |
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| Product Specific References | n/a |
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